# One Stop Microfluidics Shop

> Custom microfluidic chip manufacturing from prototype to production. Upload your design for COC, COP, PMMA, glass, PDMS & 3D-printed devices. Based in the UK; ships worldwide — Europe, North America, Singapore, and beyond.

## About

One Stop Microfluidics Shop (OSMS) is a single portal for microfluidic device manufacturing, powered by GB-Tech. We coordinate 3D printing, CNC machining, PDMS casting & moulding, glass fabrication, thermal-diffusion bonding, and injection moulding — managing every step from first prototype through to 100,000+ production units. Materials include COC (cyclic olefin copolymer), COP, PMMA, polycarbonate, PDMS, glass, and a range of biocompatible 3D-print resins. Class 7 cleanroom and ISO 13485 production are available when required. Quote turnaround within 48 hours.

## International reach

OSMS is based in the UK and ships microfluidic parts worldwide. Active customers across:

- Europe (UK, EU member states, Switzerland)
- North America (US, Canada)
- Singapore and the wider Asia-Pacific
- Customers in the Middle East and Australia on request

## Services

- Design-for-manufacture (DFM) review and routing across processes
- 3D-printed microfluidic prototypes (SLA / DLP, biocompatible resins)
- CNC-machined microfluidic chips (COC, COP, PMMA, PC)
- Injection-moulded production runs (thermoplastic and PDMS injection moulding)
- Thermal-diffusion bonding (no solvents or adhesives)
- PDMS drop-casting in CNC-machined aluminium moulds (alternative to brittle silicon wafers)
- Glass microfluidic chips for chemical resistance and optical performance
- Material selection guidance (COC, COP, PMMA, PC, PDMS, glass)
- Sterile packaging and gamma sterilisation as required

## Free Lab Tools

OSMS publishes 38+ free online calculators and tools for microfluidics and life-science researchers. They are filterable by category at /lab-tools (Microfluidics, Buffers & Dilutions, PCR & DNA, Cell Biology, Diagnostics).

- Assay Analyser — 4PL curve fit & sample interpolation for plate-reader / on-chip assays
- Primer Tm Calculator — nearest-neighbour melting temperature with salt correction
- GC Content Analyser — base composition, molecular weight, FASTA support
- Restriction Enzyme Cut Site Finder — scan DNA for 20+ common enzyme sites
- Channel Dimension Calculator — hydraulic diameter, shear stress, Reynolds number
- Residence Time Calculator — multi-segment microfluidic channel timing
- LOD/LOQ Calculator — limit of detection & quantification (blank-based & calibration curve)
- Probit LOD95 Calculator — probit regression for binary diagnostic assays (PCR, ELISA yes/no) with LOD95 confidence intervals
- Capillary Pressure Calculator — Young-Laplace equation for circular and rectangular microchannels
- Droplet Size Estimator — predict droplet diameter for T-junction and flow-focusing geometries
- Diffusion & Mixing Time Estimator — Péclet number, diffusion time, and mixing length
- Two-Phase Flow Regime Predictor — Capillary and Weber number for squeezing/dripping/jetting
- Chip Volume Calculator — total internal volume from multiple channel segments
- ELISA Plate Layout Planner — interactive 96-well plate map with auto-fill and CSV export
- Protein Molecular Weight Calculator — MW, extinction coefficient, pI from amino-acid sequence
- Buffer Recipe Calculator — PBS, Tris, HEPES, MES, Citrate, Acetate, MOPS, Bicarbonate recipes
- DNA Ligation Calculator — insert:vector molar ratio and reaction recipe
- Fluorescence Unit Converter — RFU to concentration via linear standard-curve regression
- Haemocytometer & Cell Seeding Calculator — full counting workflow with viability and plate seeding
- Doubling Time Calculator — cell growth from counts or OD with curve fitting
- Aluminium Mould Generator — generate a 4-inch CNC-ready aluminium mould from STL channel features for thermoplastic hot embossing
- Sørensen's Phosphate Buffer Calculator — Henderson-Hasselbalch pH recipe
- Oligo Reconstitution Calculator — resuspend lyophilised oligos to target concentration
- Beer-Lambert Absorbance Calculator — A=εcl for UV-Vis spectrophotometry
- Molarity & Dilution Calculator — prepare molar solutions from stock
- Reynolds Number Calculator — laminar vs turbulent flow assessment
- Serial Dilution Calculator — multi-step dilution series planner
- Flow Rate & Velocity Converter — convert between µL/min, mL/hr, etc.
- Dead Volume Calculator — tubing & connector dead-volume estimation
- Droplet Volume Calculator — droplet size from flow rates & geometry
- C1V1=C2V2 Dilution Calculator — simple dilution-equation solver
- Concentration Unit Converter — convert between molarity, mg/mL, %, etc.
- Centrifuge RCF Calculator — convert RPM to RCF (g-force)
- PCR Master Mix Calculator — reagent volumes for N reactions
- Cell Counting & Seeding Calculator — haemocytometer & seeding density
- DNA/RNA Concentration Calculator — nucleic acid quantification from A260
- Pressure Drop Calculator — Hagen-Poiseuille for microfluidic channels
- Mixing Length Calculator — diffusion-based mixing in laminar flow

## Microfluidics Jobs Board

OSMS maintains a small curated list of currently-open microfluidics roles at /jobs. Every URL is verified by an automated nightly checker; expired postings are auto-flagged and the apply link is hidden. Roles span industry and academic positions across Europe, North America, and Asia-Pacific.

## Applications

OSMS publishes commercial-intent application landing pages describing the microfluidic devices we manufacture for each field, at /applications:

- Diagnostics & IVD — /applications/diagnostics-ivd
- Drug Delivery & Nanoparticles (incl. LNPs) — /applications/drug-delivery
- Organ-on-a-Chip — /applications/organ-on-a-chip
- Cell Biology & Single-Cell — /applications/cell-biology
- PCR & qPCR — /applications/pcr-qpcr
- Extracellular Vesicle & Exosome Isolation — /applications/extracellular-vesicles
- Environmental & Food Testing — /applications/environmental-monitoring

## Blog

OSMS maintains a large, cross-linked library of 40+ technical articles at /blog, spanning microfluidics fundamentals, materials, engineering and manufacturing. Examples:

- Fundamentals — what is microfluidics, lab-on-a-chip, laminar flow & the Reynolds number, droplet microfluidics
- Materials — COC vs COP vs PMMA, PDMS, glass chips, chemical compatibility of microfluidic plastics, optical properties (transmission & autofluorescence)
- Engineering — microchannel aspect ratio & design rules, surface roughness, burst pressure & bond strength, dead volume, pressure drop in microchannels
- Manufacturing — injection moulding, CNC micromachining, 3D printing, soft lithography, bonding methods, laser welding
- Partnership: OSMS × PPTechSales × MicroDrop — microfluidic distribution and instrumentation

## Links

- Homepage: https://www.one-stop-microfluidics-shop.com/
- Services: https://www.one-stop-microfluidics-shop.com/services
- PDMS Moulds: https://www.one-stop-microfluidics-shop.com/pdms-moulds
- Lab Tools: https://www.one-stop-microfluidics-shop.com/lab-tools
- Applications: https://www.one-stop-microfluidics-shop.com/applications
- Resources: https://www.one-stop-microfluidics-shop.com/resources
- Blog: https://www.one-stop-microfluidics-shop.com/blog
- Jobs: https://www.one-stop-microfluidics-shop.com/jobs
- Insights: https://www.one-stop-microfluidics-shop.com/insights
- Upload Design: https://www.one-stop-microfluidics-shop.com/upload
- Book a 30-min call: https://www.one-stop-microfluidics-shop.com/book
- Request NDA: https://www.one-stop-microfluidics-shop.com/nda
- Sitemap: https://www.one-stop-microfluidics-shop.com/sitemap.xml
- robots.txt: https://www.one-stop-microfluidics-shop.com/robots.txt